Publications

Iqbal SM, Aufy M, Shabbir W, Lemmens-Gruber R. Identification of phosphorylation sites and binding pockets for modulation of NaV 1.5 channel by Fyn tyrosine kinase. The FEBS Journal. 2018 Jul;285(13):2520-2530. doi.org/10.1111/febs.14496

Willam A, Aufy M, Tzotzos S, Evanzin H, Chytracek S, Geppert S et al. Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants. Frontiers in Pharmacology. 2017;8. 85. doi.org/10.3389/fphar.2017.00085

Willam A, Aufy M, Tzotzos S, El-Malazi D, Poser F, Wagner A et al. TNF Lectin-Like Domain Restores Epithelial Sodium Channel Function in Frameshift Mutants Associated with Pseudohypoaldosteronism Type 1B. Frontiers in Immunology. 2017;8. 601. doi.org/10.3389/fimmu.2017.00601

Lucas R, Yue Q, Alli A, Duke BJ, Al-Khalili O, Thai TL et al. The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit. Journal of Biological Chemistry. 2016 Nov 4;291(45):23440-23451. doi.org/10.1074/jbc.M116.718163

Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M et al. Glycosylation-dependent activation of epithelial sodium channel by solnatide. Biochemical Pharmacology. 2015 Dez 15;98(4):740-753. doi.org/10.1016/j.bcp.2015.08.003