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Iqbal SM, Lemmens-Gruber R. Phosphorylation of cardiac voltage-gated sodium channel: Potential players with multiple dimensions. Acta Physiologica. 2019 Mär;225(3):e13210. Epub 2018. doi: 10.1111/apha.13210
Simeone X, Karch R, Ciuraszkiewicz A, Orr-Urtreger A, Lemmens-Gruber R, Scholze P et al. The role of the nAChR subunits α5, β2, and β4 on synaptic transmission in the mouse superior cervical ganglion. Physiological Reports. 2019 Mär;7(6):e14023. doi: 10.14814/phy2.14023
Iqbal SM, Aufy M, Shabbir W, Lemmens-Gruber R. Identification of phosphorylation sites and binding pockets for modulation of NaV 1.5 channel by Fyn tyrosine kinase. The FEBS Journal. 2018 Jul;285(13):2520-2530. doi: 10.1111/febs.14496
Heilos D, Röhrl C, Pirker C, Englinger B, Baier D, Mohr T et al. Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins. Oncotarget. 2018;9(39):25661-25680. doi: 10.18632/oncotarget.25432
Heilos D, Rodríguez-Carrasco Y, Englinger B, Timelthaler G, van Schoonhoven S, Sulyok M et al. The Natural Fungal Metabolite Beauvericin Exerts Anticancer Activity In Vivo: A Pre-Clinical Pilot Study. Toxins. 2017 Aug 24;9(9):258. doi: 10.3390/toxins9090258
Iqbal SM, Lemmens-Gruber R. Voltage gated ion channels blockade is the underlying mechanism of BIMU8 induced cardiotoxicity. Toxicology Letters. 2017 Aug 5;277:64-68. doi: 10.1016/j.toxlet.2017.05.024
Willam A, Aufy M, Tzotzos S, El-Malazi D, Poser F, Wagner A et al. TNF Lectin-Like Domain Restores Epithelial Sodium Channel Function in Frameshift Mutants Associated with Pseudohypoaldosteronism Type 1B. Frontiers in Immunology. 2017 Mai 29;8:601. doi: 10.3389/fimmu.2017.00601
Willam A, Aufy M, Tzotzos S, Evanzin H, Chytracek S, Geppert S et al. Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants. Frontiers in Pharmacology. 2017 Feb 24;8:85. doi: 10.3389/fphar.2017.00085
Lucas R, Yue Q, Alli A, Duke BJ, Al-Khalili O, Thai TL et al. The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit. Journal of Biological Chemistry. 2016 Nov 4;291(45):23440-23451. doi: 10.1074/jbc.M116.718163
Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M et al. Glycosylation-dependent activation of epithelial sodium channel by solnatide. Biochemical Pharmacology. 2015 Dez 15;98(4):740-753. doi: 10.1016/j.bcp.2015.08.003
Dornetshuber-Fleiss R, Heilos D, Mohr T, Richter L, Süssmuth RD, Zlesak M et al. The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo. Biochemical Pharmacology. 2015 Feb 1;93(3):318-331. doi: 10.1016/j.bcp.2014.12.013
Hana M, Lemmens-Gruber R, Watschinger B, Stemer G. Dosing accuracy and potential drug-drug interactions in haemodialysis patients. International Journal of Clinical Pharmacy. 2015 Feb;37(1):183-184.
Iqbal SM, Andavan GSB, Lemmens-Gruber R. Differential modulation of fast inactivation in cardiac sodium channel splice variants by Fyn tyrosine kinase. Cellular Physiology and Biochemistry. 2015;37(3):825-837. doi: 10.1159/000430211
Chu NK, Shabbir W, Bove-Fenderson E, Araman MC, Lemmens R, Harris DA et al. A C-terminal Membrane Anchor Affects the Interactions of Prion Proteins with Lipid Membranes. Journal of Biological Chemistry. 2014 Okt 24;289(43):30144-30160. doi: 10.1074/jbc.M114.587345
Jungwirth U, Gojo J, Tuder T, Walko G, Holcmann M, Schoefl T et al. Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46. Molecular Cancer Therapeutics. 2014 Okt;13(10):2436-2449. doi: 10.1158/1535-7163.MCT-14-0087
Petrak J, Lemmens-Gruber R, Watschinger B, Stemer G. DRUG INTERACTIONS IN KIDNEY TRANSPLANT PATIENTS - MORE THAN A DATABASE QUERY! Transplant international. 2014 Okt;27(S 4):12-12. 34.
Stemer G, Gnam B, Gross M, Lemmens-Gruber R, Ristl R, Watschinger B. "PILL BURDEN", AGE OR EDUCATION? - WHAT FACTORS INFLUENCES THE MEDICATION KNOWLEDGE AND THE ADHERENCE OF KIDNEY TRANSPLANT PATIENTS? Transplant international. 2014 Okt;27:12-12.
Czikora I, Alli A, Bao H-F, Kaftan D, Sridhar S, Apell H-J et al. A Novel Tumor Necrosis Factor-mediated Mechanism of Direct Epithelial Sodium Channel Activation. American Journal of Respiratory and Critical Care Medicine. 2014 Sep 1;190(5):522-532. doi: 10.1164/rccm.201405-0833OC
Stemer G, Gnam B, Groß M, Lemmens-Gruber R, Ristl R, Watschinger B. Pill Burden, Age or Education - What Impacts On Medication Knowledge and Adherence to Immunosuppressive Therapy in Kidney Transplant Recipients (KTRs)? American Journal of Transplantation. 2014 Jun;14(S 3):616-616. D2431. doi: 10.1111/ajt.12890
Shabbir W, Hazemi Gavasaraei P, Tzotzos SJ, Fischer B, Fischer H, Pietschmann H et al. Mechanism of Action of Novel Lung Edema Therapeutic AP301 by Activation of the Epithelial Sodium Channel. Molecular Pharmacology. 2013 Dez;84(6):899-910. doi: 10.1124/mol.113.089409
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