We strive to gain mechanistic insights into the dynamics of protein networks underlying vertebrate somatosensation in health, development (aging), and disease (chronic pain) – an endeavor, which lies at the heart of both understanding the molecular signature of chronic pain and identifying novel drug targets.

Drug Screening

Bone Pharmacology

Our research focuses on ion channel structure and dynamics using computational methods. A major goal is to identify drug candidates for rare ion channel diseases. Hypotheses developed by our computational approaches are tested in close collaboration with experimental laboratories.