Post docs

Feng Xian, PhD

room: 2D347

tel: +43 1 4277 55306

e-mail: feng.xian@univie.ac.at

Feng Xian

Publications

Grundtner S , Xian F, Malzl D, Radits T, Barry AM, Sondermann JR et al. Temporal and demographic patterns of peripheral nerve proteomes in preclinical neuropathic pain. Biomedicine & Pharmacotherapy. 2025 Dez 4;193:118855. doi: 10.1016/j.biopha.2025.118855

Haiss P, Liu R, Xian F , Varela DG , Schmidt M , Dirsch VM et al. Evodiamine induces centrosome amplification with subsequent G2/M cell cycle arrest in primary vascular smooth muscle cells. Biochemical Pharmacology. 2025 Dez;242(Pt 2):117320. doi: 10.1016/j.bcp.2025.117320

Barry AM, Sondermann JR, Lesnak JB, Xian F, Franco-Enzástiga Ú, O’Brien JA et al. Multi-omic integration with human dorsal root ganglia proteomics highlights TNFα signalling as a relevant sexually dimorphic pathway. Pain. 2025 Okt 1;166(10):2386-2402. doi: 10.1097/j.pain.0000000000003656

Xian F, Brenek M, Krisp C, Urbauer E, Kumar RKR, Aguanno D et al. Ultra-sensitive metaproteomics redefines the dark metaproteome, uncovering host-microbiome interactions and drug targets in intestinal diseases. Nature Communications. 2025 Jul 18;16:6644. doi: 10.1038/s41467-025-61977-7

Sondermann JR, Barry A, Xian F, Haberl T, Gomez Varela D, Benseler F et al. Proximity labelling reveals the compartmental proteome of murine sensory neurons. bioRxiv. 2025 Jun, S. 1-53. doi: 10.1101/2025.06.13.659475

Xian F, Brenek M, Krisp C, Aguanno D, Urbauer E, Srikumar T et al. Ultra-sensitivity metaproteomics redefines the gut “dark metaproteome”, uncovering host-microbiome interactions and drug targets in intestinal inflammatory diseases. bioRxiv. 2025 Jan 10. doi: 10.1101/2024.04.22.590295

Grundtner S, Sondermann JR, Xian F, Malzl D, Segelcke D, Pogatzki-Zahn EM et al. Deep proteomics and network pharmacology reveal sex- and age-shared neuropathic pain signatures in mouse dorsal root ganglia. Pharmacological Research. 2024 Dez;211:107552. Epub 2024 Dez 16. doi: 10.1016/j.phrs.2024.107552

Urbauer E, Aguanno D, Mindermann N, Omer H, Metwaly A, Krammel T et al. Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease. Cell Host & Microbe. 2024 Aug 14;32(8):1347-1364.e10. doi: 10.1016/j.chom.2024.06.013

Barry A, Sondermann JR, Lesnak J, Xian F, Franco-Enzástiga Ú, O’Brien J et al. Multi-omic integration with human DRG proteomics highlights TNFα signalling as a relevant sexually dimorphic pathway. bioRxiv. 2024. doi: 10.1101/2024.12.06.626968

Gómez-Varela D , Xian F , Grundtner S, Sondermann JR, Carta G , Schmidt M. Increasing taxonomic and functional characterization of host-microbiome interactions by DIA-PASEF metaproteomics. Frontiers in Microbiology. 2023 Okt;14:1258703. doi: 10.3389/fmicb.2023.1258703

Xian F, Sondermann JR, Gomez Varela D , Schmidt M. Deep proteome profiling reveals signatures of age and sex differences in paw skin and sciatic nerve of naïve mice. eLife. 2022 Nov 30;11:e81431. doi: 10.7554/eLife.81431