Professors
Head
Univ. Prof. Manuela Schmidt, Ph.D
room: 2D349
tel: +43-1-4277-55360
e-mail: manuela_schmidt@univie.ac.at
Research: Systems Biology of Pain
Teaching: more information
Funktionen
- Vizedekanin - Fakultät für Lebenswissenschaften
- stv. Leiterin - Department für Pharmazeutische Wissenschaften
Manuela Schmidt (photo: Frank Stefan Kimmel)
Publikationen
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Pogatzki-Zahn EM, Gomez-Varela D, Erdmann G, Kaschube K, Segelcke D, Schmidt M. A proteome signature for acute incisional pain in dorsal root ganglia of mice. Pain. 2021 Jul;162(7):2070-2086. doi: 10.1097/j.pain.0000000000002207
Michel N, Narayanan P, Shomroni O, Schmidt M. Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction. Cell Reports. 2020 Jul 21;32(3):107912. doi: 10.1016/j.celrep.2020.107912
Sondermann JR, Barry AM, Jahn O, Michel N, Abdelaziz R, Kügler S et al. Vti1b promotes TRPV1 sensitization during inflammatory pain. Pain. 2019 Feb 1;160(2):508-527. doi: 10.1097/j.pain.0000000000001418
Gomez-Varela D, Barry AM, Schmidt M. Proteome-based systems biology in chronic pain. Journal of Proteomics. 2019 Jan 6;190:1-11. Epub 2018 Apr 10. doi: 10.1016/j.jprot.2018.04.004
Barry AM, Sondermann JH, Sondermann JH, Gomez-Varela D, Schmidt M. Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord. Frontiers in molecular neuroscience. 2018 Aug 14;11:259. doi: 10.3389/fnmol.2018.00259
Narayanan P, Hütte M, Kudryasheva G, Taberner FJ, Lechner SG, Rehfeldt F et al. Myotubularin related protein-2 and its phospholipid substrate PIP <inf>2</inf> control Piezo2-mediated mechanotransduction in peripheral sensory neurons. eLife. 2018 Mär 9;7:e32346. doi: 10.7554/eLife.32346
Dembla S, Behrendt M, Mohr F, Goecke C, Sondermann J, Schneider FM et al. Anti-nociceptive action of peripheral mu- opioid receptors by G-beta-gamma protein-mediated inhibition of TRPM3 channels. eLife. 2017 Aug 15;6:e26280. doi: 10.7554/eLife.26280
Avenali L, Abate Fulas O, Sondermann J, Narayanan P, Gomez-Varela D, Schmidt M. Nocistatin sensitizes TRPA1 channels in peripheral sensory neurons. Channels. 2017;11(1):11-19. Epub 2016 Jul. doi: 10.1080/19336950.2016.1207025
Gomez-Varela D, Schmidt M. Exploring novel paths towards protein signatures of chronic pain. Molecular Pain. 2016 Dez;12. doi: 10.1177/1744806916679658
Narayanan P, Sondermann J, Rouwette T, Karaca S, Urlaub H, Mitkovski M et al. Native Piezo2 interactomics identifies pericentrin as a novel regulator of Piezo2 in somatosensory neurons. Journal of Proteome Research. 2016 Aug 5;15(8):2676-2687. Epub 2016 Jul. doi: 10.1021/acs.jproteome.6b00235
Rouwette T, Avenali L, Sondermann J, Narayanan P, Gomez-Varela D, Schmidt M. Modulation of nociceptive ion channels and receptors via protein-protein interactions: Implications for pain relief. Channels. 2015 Jul;9(4):175-185. doi: 10.1080/19336950.2015.1051270
Coste B, E. Murthy S, Mathur J, Schmidt M, Mechioukhi Y, Delmas P et al. Piezo1 ion channel pore properties are dictated by C-terminal region. Nature Communications. 2015 Mai;6:7223. doi: 10.1038/ncomms8223
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