Senior Scientist

Dr. David Gomez Varela

room: 2D351

tel: +43 1 4277 55361

e-mail: david.gomez.varela@univie.ac.at

Personal Homepage: https://homepage.univie.ac.at/david.gomez.varela/

Director of the Center of Excellence for Metaproteomics

David Gomez Varela (photo: MPIem)

 Publications

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Grundtner S, Sondermann JR, Xian F, Malzl D, Segelcke D, Pogatzki-Zahn EM et al. Deep proteomics and network pharmacology reveal sex- and age-shared neuropathic pain signatures in mouse dorsal root ganglia. Pharmacological Research. 2024 Dez;211:107552. Epub 2024 Dez 16. doi: 10.1016/j.phrs.2024.107552

Urbauer E, Aguanno D, Mindermann N, Omer H, Metwaly A, Krammel T et al. Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease. Cell Host & Microbe. 2024 Aug 14;32(8):1347-1364.e10. doi: 10.1016/j.chom.2024.06.013

Klén R, Huespe IA, Gregalio FA, Lalueza Blanco AL, Pedrera Jimenez M, Garcia Barrio N et al. Development and validation of COEWS (COVID-19 Early Warning Score) for hospitalized COVID-19 with laboratory features: A multicontinental retrospective study. eLife. 2023 Aug 24;12:e85618. doi: 10.7554/eLife.85618

Huespe IA, Ferraris A, Lalueza A, Valdez PR, Peroni ML, Cayetti LA et al. COVID-19 vaccines reduce mortality in hospitalized patients with oxygen requirements: Differences between vaccine subtypes. A multicontinental cohort study. Journal of medical virology. 2023 Mai 15;95(5):e28786. doi: 10.1002/jmv.28786

Segelcke D, van der Burgt M, Kappert C, Schmidt Garcia D, Sondermann JR, Bigalke S et al. Phenotype- and species-specific skin proteomic signatures for incision-induced pain in humans and mice. British Journal of Anaesthesia (BJA). 2023 Mär;130(3):331-342. Epub 2023 Jan 5. doi: 10.1016/j.bja.2022.10.040

Schmidt M, Sondermann JR, Gomez-Varela D, Çubuk C, Millet Q, Lewis MJ et al. Transcriptomic and proteomic profiling of NaV1.8-expressing mouse nociceptors. Frontiers in molecular neuroscience. 2022 Okt 11;(15):1002842. doi: 10.3389/fnmol.2022.1002842

Klen R, Purohit D, Gomez-Huelgas R, Casas-Rojo JM, Anton-Santos JM, Nunez-Cortes JM et al. Development and evaluation of a machine learning-based in-hospital COVID-19 disease outcome predictor (CODOP): A multicontinental retrospective study. eLife. 2022 Mai 17;11:e75985. doi: 10.7554/eLife.75985

Segelcke D, Burgt MVD, Kappert C, Schmidt-Garcia D, Sondermann JR, Bigalke S et al. Species-specific cutaneous protein signatures upon incision injury and correlation with distinct pain-related phenotypes in humans. bioRxiv. 2022 Mär 8. doi: 10.1101/2022.03.07.482980

Pogatzki-Zahn EM, Gomez-Varela D, Erdmann G, Kaschube K, Segelcke D, Schmidt M. A proteome signature for acute incisional pain in dorsal root ganglia of mice. Pain. 2021 Jul;162(7):2070-2086. doi: 10.1097/j.pain.0000000000002207

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