Research Groups

• Systems Biology of Pain

  We strive to gain mechanistic insights into the dynamics of protein networks underlying vertebrate somatosensation in health, development (aging), and disease (chronic pain) – an endeavor, which lies at the heart of both understanding the molecular signature of chronic pain and identifying novel drug targets.

• Cerebrovascular Pharmacology

  We aim to better understand the etiology and pathophysiology of cerebrovascular disease and brain aging to identify novel druggable targets and to develop innovative therapies for prevention, cytoprotection, regeneration, and recovery of motor and cognitive function.

• Computational Pharmacology

  Our research aims to uncover rare disease mechanisms through an atomistic understanding of protein dynamics, molecular interactions, and how disease-associated variants reshape conformational landscapes and interaction networks.

• Molecular Disease Mechanisms

  We are passionate about the molecular mechanisms of neuronal circuit formation and function. Our research focuses on neuronal non-coding RNAs in the context of neuropsychiatric and neurodevelopmental disorders, and aims to uncover novel therapeutic approaches for diseases of the nervous system.